Abdullah, Vera Iriani and Rusyanti, Siti and Sumarni, Sumarni and Rosdianto, Nuur Octascriptiriani and Ilyas, Erlina and Nur, Fatiyani and Mardiani, Dita Eka (2022) Gel Formulation Test of Gotu Kola Leaf Extract (Centella Asiatica) 15% For Handling Striae Gravidarum. Journal of Pharmaceutical Negative Results, 13 (4). ISSN 2229-7723
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Abstract
Hormonal changes during pregnancy will impact the skin so that the skin of pregnant women will be vulnerable and at significant risk for striae gravidarum in several areas of the body, including the abdomen, breasts, calves, and thighs. This will impact the quality of life, the incidence of pelvic organ prolapses, and rupture of the perineum due to a lack of collagen in the body. Techniques for treating striae gravidarum have been developed in several methods, including micro-needling and fractional CO2 laser, vitamin C, the use of 0.1% tretinoin cream to the use of frequency radio microneedle (FMR). This treatment aims to help increase, maintain and stabilize collagen in the skin. Gotu kola leaf (Centella Asiatica) is one of the plants that can stimulate the production of collagen I and moisturize the skin because it contains compounds such as saponins, asiaticoside, Asiatic acid, madecassoside, and triterpenes. This plant is also anti-infectious, anti-leprosy, anti-syphilis, and skin cell revitalization. This study aimed to test the effectiveness of a gel based on Gotu kola leaf with a concentration of 15% for treating striae gravidarum. This research method is quasi-experimental with a one-group pre-test post-test design. The population and research sample consisted of 3 respondents; each respondent was assessed in 4 areas: the breast, abdomen, thigh, and calf. The results show that because the significance level is more significant than α (0.130 > 0.05), there is not enough reason to accept H0, and we also get the difference between the average value before and after being given a 15% concentration, which is 1.5, which means the average decreases. Conclusion Gel preparations of Gotu kola leaf extract (Centella Asiatica) with a concentration of 15% are effective in treating striae gravidarum degrees 1,2, and 3.
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| Uncontrolled Keywords: | Skin of pregnant women, medicinal plants, Cosmetic disorders | ||||||||||||||||||||||||||||||||
| Subjects: | R Medicine > RG Gynecology and obstetrics R Medicine > RT Nursing |
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| Divisions: | Jurusan Kebidanan > D4 Kebidanan | ||||||||||||||||||||||||||||||||
| Depositing User: | Dita Eka M | ||||||||||||||||||||||||||||||||
| Date Deposited: | 17 Feb 2023 11:31 | ||||||||||||||||||||||||||||||||
| Last Modified: | 17 Feb 2023 11:31 | ||||||||||||||||||||||||||||||||
| URI: | http://repo.poltekkestasikmalaya.ac.id/id/eprint/1618 |
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